WEGENER GRAN�LOMATOZU: TANISAL ZORLUK YA�ANAN B�R OLGU NEDEN�YLE T�RK�YE'DEN B�LD�R�LEN OLGULARIN L�TERAT�R E�L���NDE �NCELENMES�

YAPICIO�LU, Sena; ERER, Onur Fevzi; YAL�IN, Yavuz Alp; AKTO�U �ZKAN, �erir

Cilt : 37 Say� : 3 Y�l : 2023

37/3Son Say� Erken Bask� Ar�iv Pop�ler Makaleler

Yazar Katk� Formu

WEGENER GRAN�LOMATOZU: TANISAL ZORLUK YA�ANAN B�R OLGU NEDEN�YLE T�RK�YE'DEN B�LD�R�LEN OLGULARIN L�TERAT�R E�L��NDE �NCELENMES� [G��s Hastanesi Dergisi]

G��s Hastanesi Dergisi. 2004; 18(1): 33-40

WEGENER GRAN�LOMATOZU: TANISAL ZORLUK YA�ANAN B�R OLGU NEDEN�YLE T�RK�YE'DEN B�LD�R�LEN OLGULARIN L�TERAT�R E�L��NDE �NCELENMES�

Sena YAPICIO�LU¹, Onur Fevzi ERER¹, Yavuz Alp YAL�IN¹, �erir AKTO�U �ZKAN¹
G��s Hastal�klar� ve Cerrahisi E�itim ve Ara�t�rma Hastanesi, �zmir

Wegener gran�lomatozu (WG) �zellikle �st ve alt solunum yollar� ile b�brekleri tutabilen nekro-tizan gran�lomat�z vask�lit�e tan�mlanan nadir g�r�len bir hastal�kt�r. T�rkiye'de g�r�lme s�kl��n� bildiren �ok olgulu yay�n yoktur. Biz de bu ama�la de�i�ik klinik ve radyolojik bulgularla klini�imize ba�vuran bir WG olgusunu T�rkiye'den bildirilen 23 olgunun �zellikleriyle birlikte inceledik. Olgumuz atipik prezantasyonu, nekrotizan gran�lomat�z inflamasyon patolojik tan�s�yla �nce t�berk�loz tedavisi alm�� olup daha sonraki klinik seyriyle ve c-ANCA pozitifli�i ve patolojik bulgular�yla WG tan�s� alm��t�r ve tedavi ba�lanm��t�r. Halen tedavisinin 7. ay�nda olup remisyonda ve izlenmektedir.

Anahtar Kelimeler: Wegener gran�lomatozu, akci�er tutulumu, c-ANCA

WEGENER GRANULOMATOSIS: EVALUATION OF ONE CASE HAVING DIAGNOSTIC DIFFICULTY AND THE OTHER CASES PUBLISHED IN TURKEY

Sena YAPICIO�LU¹, Onur Fevzi ERER¹, Yavuz Alp YAL�IN¹, �erir AKTO�U �ZKAN¹
G��s Hastal�klar� ve Cerrahisi E�itim ve Ara�t�rma Hastanesi, �zmir

Wegener granulomatosis (WG) is a necrotising granulomatous vasculitic disease that especially involves upper and lower respiratory tract and kidney. Its incidence is rare and there is not any literature with many cases about its incidence in Turkey. For these reason we investigated the characteristics of twentythree WG cases from published data in Turkey with those of our one case admitted to our clinic with different clinical and radiological findings. Firstly our case diagnosed as tuberculosis because of its atypical presentation and treated antitubercosis drugs but later it was diagnosed as WG with clinical course, radiological and pathological findings and pozitivity of c-AMCA. It is in remission at 7th month of treatment and being followed up to present.

Keywords: Wegener granulomatosis, lung involvement, c-ANCA

Makale Dili: T�rk�e

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WEGENER GRAN�LOMATOZU: TANISAL ZORLUK YA�ANAN B�R OLGU NEDEN�YLE T�RK�YE'DEN B�LD�R�LEN OLGULARIN L�TERAT�R E�L���NDE �NCELENMES�

WEGENER GRANULOMATOSIS: EVALUATION OF ONE CASE HAVING DIAGNOSTIC DIFFICULTY AND THE OTHER CASES PUBLISHED IN TURKEY

WEGENER GRAN�LOMATOZU: TANISAL ZORLUK YA�ANAN B�R OLGU NEDEN�YLE T�RK�YE'DEN B�LD�R�LEN OLGULARIN L�TERAT�R E�L��NDE �NCELENMES�