PLEVRAL T�BERK�LOZLU HASTALARDA YA� VE C�NS�YETE G�RE PLEVRA SIVISI ADA D�ZEY�N�N KAR�ILA�TIRILMASI

DEN�Z, Sami; ERBAYCU, Ahmet Emin; Onur G��SAV, Mutlu; AL�ZORO�LU, Dursun; POLAT, G�lru; DEREL�, Mustafa �evket

Cilt : 33 Ek : 3 Y�l : 2023

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PLEVRAL T�BERK�LOZLU HASTALARDA YA� VE C�NS�YETE G�RE PLEVRA SIVISI ADA D�ZEY�N�N KAR�ILA�TIRILMASI [G��s Hastanesi Dergisi]

G��s Hastanesi Dergisi. 2019; 33(3): 153-160

PLEVRAL T�BERK�LOZLU HASTALARDA YA� VE C�NS�YETE G�RE PLEVRA SIVISI ADA D�ZEY�N�N KAR�ILA�TIRILMASI

Sami DEN�Z¹, Ahmet Emin ERBAYCU¹, Mutlu Onur G��SAV¹, Dursun AL�ZORO�LU¹, G�lru POLAT¹, Mustafa �evket DEREL�¹
Sa�l�k Bilimleri �niversitesi �zmir Dr Suat Seren G��s Hastal�klar� ve Cerrahisi E�itim ve Ara�t�rma Hastanesi, G�g�s Hastal�klar�, �zmir, T�rkiye

Ama�: Tan� ve tedavideki geli�melere ra�men, t�berk�loz (TB) �lkemizde oldu�u gibi t�m d�nyada da �nemli bir mortalite ve mortalite nedenidir. �al��mam�zda; TB pl�rezi bulunan hastalarda plevral s�v� ADA d�zeyinin ya� ve cinsiyet ile ili�kisinin belirlenmesi ama�land�. Y�ntem ve Gere�: �al��ma retrospektif bir �al��ma olarak tasarlanm��t�r. Hastalar�n ya��, solunum fonksiyon testleri (SFT), periferik kanda; glikoz, protein, alb�min, aspartat aminotransferaz (AST), alanin aminotransferaz (ALT), alkalen fosfataz (ALP), laktat dehidrojenaz (LDH), bilirubin, �re, kreatinin ve kan h�cre say�m�; kan gaz� analizi, plevral s�v�da; glukoz, alb�min, protein, LDH, adenosin deaminaz (ADA) ve s�v� h�cre say�m� sonu�lar� kaydedildi. Bulgular: �al��maya toplam 41'i kad�n, 105'i erkek 145 hasta dahil edildi,. Hastalar�n ya� ortalamas� 53.1, ortalama plevral s�v� ADA d�zeyi 55.2 idi. Cinsiyete a��s�ndan kar��la�t�r�ld��nda; plevral s�v� ADA d�zeyleri kad�nlarda anlaml� olarak d��kt� (p = 0.031). Hastalar 65 ya��ndan k��k ve b�y�k olarak ayr�ld��nda, plevral s�v� ADA d�zeyi aras�nda fark yoktu (p = 0.657). Sonu�: T�berk�loz plevral ef�zyonlarda adenosin deaminaz d�zeyi cinsiyete g�re de�i�mekte ve kad�nlarda erkeklere g�re daha d��k oldu�u saptanm��t�r. 65 ya� alt� ve �st� gruplar aras�nda benzer seviyelerde bulunmu�tur.

Anahtar Kelimeler: T�berk�loz; adenozin deaminaz; ya�; cinsiyet

COMPARISON OF PLEURAL FLUID ADA LEVEL IN TERMS OF AGE AND GENDER OF PATIENTS WITH PLEURAL TUBERCULOSIS

Aim: Despite improvements in the diagnosis and treatment, tuberculosis (TB) is still an important cause of morbidity and mortality all over the world, as it is in our country. Aim: It was aimed to determine the relation of pleural fluid adenosine deaminase (ADA) level with age and gender of patients with TB pleurisy. Material and Methods: The study was designed as a retrospective study. Age of the patients, pulmonary function tests (PFT) measurements, glucose, protein, albumin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), bilirubin, urea, creatinine and blood cell count from peripheral blood; blood gas analysis, glucose, albumin, protein, LDH, ADA, fluid cell count results in pleural fluid were recorded. Results: A total of 145 patients were included in the study, 41 were female and 105 were male. The mean age of the patients was 53.1 years, the mean pleural fluid ADA level was 55.2. When compared to gender; pleural fluid ADA levels were significantly lower in women (p = 0.031). When patients were divided as younger and older than 65 years old, there was no difference in pleural fluid ADA level (p = 0.657). Conclusion: The level of adenosine deaminase in tuberculous pleural effusions varies according to gender and was detected lower in females than in males. Similar levels were found between the groups above and under 65 years old.

Keywords: Tuberculosis; adenosine deaminase; age; gender

Makale Dili: T�rk�e

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