K�TLE �EKL�NDE PREZENTE OLAN AMIODARONA BA�LI B�R ORGAN�ZE PN�MON� OLGUSU

B�Y�K��R�N, Melih; ANAR, Ceyda; YAVA�O�LU, G�nhan; HAL�L�OLAR, H�seyin; Y�CEL, Nur

Cilt : 25 Ek : 3 Y�l : 2023

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�zmir G��s Hastanesi Dergisi

K�TLE �EKL�NDE PREZENTE OLAN AMIODARONA BA�LI B�R ORGAN�ZE PN�MON� OLGUSU [G��s Hastanesi Dergisi]

G��s Hastanesi Dergisi. 2011; 25(3): 177-181

K�TLE �EKL�NDE PREZENTE OLAN AMIODARONA BA�LI B�R ORGAN�ZE PN�MON� OLGUSU

Melih B�Y�K��R�N¹, Ceyda ANAR¹, G�nhan YAVA�O�LU¹, H�seyin HAL�L�OLAR¹, Nur Y�CEL²
¹�zmir Dr. Suat Seren G��s Hastal�klar� ve Cerrahisi E�itim ve Ara�t�rma Hastanesi, G��s Hastal�klar�, �ZM�R
²�zmir Dr. Suat Seren G��s Hastal�klar� ve Cerrahisi E�itim ve Ara�t�rma Hastanesi, Patoloji B�l�m�, �zmir

Amiodaron pulmoner fibrozise gidebilecek intertisyel pn�moniye neden olan antiaritmik bir ila�t�r. Altm�� d�rt ya��nda dispne, ate�, �ks�r�k yak�nmas� ile ba�vuran erkek hastan�n �zge�mi�inden amiodaron, metoprolol ve aspirin ila�lar�n� kulland�� renildi. Y�ksek rezol�syonlu bilgisayarl� tomografisinde (YRBT) bilateral �st loblarda lokalize konsolidasyon g�r�n�ml� lezyonlar�n olmas� ve tru-cut doku biyopsisinin organize pn�moni olarak yorumlanmas� sonucunda hastada amiodarona ba�l� pulmoner toksisite d��n�ld�. Steroid tedavisi ba�land�ktan �� ay sonra �ekilen g��s radyogram�nda tam regresyon izlendi. Bu olguda YRBT'de amiodaron toksisitesinin en s�k g�r�len bulgusu olan bilateral intertisyel infiltratlar yerine daha nadir g�r�len iyi lokalize edilen kitle ve konsolidasyon g�r�n�mlerin de olabilece�i vurgulanm��t�r. Ayr�ca solunum sistemi yak�nmalar� ile gelen hastalarda �yk� al�rken kullanmakta oldu�u ila�lar� detayl� bir �ekilde sorgulamakta yarar oldu�unu d��nmekteyiz.

Anahtar Kelimeler: Amiodaron, organize pn�moni, akci�er, konsolidasyon, kitle, toksisite

A CASE OF AMIODARONE INDUCED ORGANIZING PNEUMONIA PRESENTING AS A PULMONARY MASS

Amiodarone is an antiarrhythmic drug that can cause interstitial pneumonitis leading to pulmonary fibrosis. Amiodarone, metoprolol, and aspirin drugs had been used by a 64 year old man who admitted with dyspnea, fever, cough. Bilateral localized consolidation lesion was in upper lobes in high resolution computed tomography ( HRCT) and tru- cut tissue biyopsy was reported as organizing pneumonia; so amiodarone-induced pulmonary toxicity was thought in the patient. Three months after cessation of steroid treatment, chest radyogram shows complete regression of pneumonitis. The present case report demonstrates the localized mass, and consolidation lesions that is seen very rare instead of bilateral interstitial infiltrates that is the most common HRCT findings of amiodarone toxicity. In addition, we thougt that drugs that has been used must cross-examine in detail in the patients admitted with respiratory symptoms.

Keywords: Amiodaron, organizing pneumonia,pulmonary,consolidation,mass, toxicity

Melih B�Y�K��R�N, Ceyda ANAR, G�nhan YAVA�O�LU, H�seyin HAL�L�OLAR, Nur Y�CEL. A CASE OF AMIODARONE INDUCED ORGANIZING PNEUMONIA PRESENTING AS A PULMONARY MASS . G��s Hastanesi Dergisi. 2011; 25(3): 177-181
Makale Dili: T�rk�e

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